EGFR/VEGFR2-IN-4 - CAS 870962-74-6

EGFR/VEGFR2-IN-4 (Compound 19) is an irreversible inhibitor of both EGFR and VEGFR-2, exhibiting IC50 values of 18.7 nM and 102.3 nM, respectively, under conditions of 1 μM ATP.

EGFR, VEGFR

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

870882

C29H29N5O5

527.57

N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CN1)C=3C(=O)C=C(OCC4=CC=CC=C4)C(=O)C3

-20°C

Ice Packs

Small Compound