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Molfinity

EHT 1610 - CAS 1425945-60-3

EHT 1610 - CAS 1425945-60-3

SKU:MF-0032789-01

Regular price $96.50 USD
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  • Bioactivity

    EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.

  • Target

    DYRK, GSK-3, NF-κB, Tyrosinase, CDK

  • Related Pathways

    Tyrosine Kinase/Adaptors, NF-κB, Proteases/Proteasome, PI3K/Akt/mTOR signaling, Stem Cells, Cell Cycle/Checkpoint

  • CAS Number

    1425882

  • Purity

    0.9859

  • Molecular Formula

    C18H14FN5O2S

  • Molecular Weight

    383.4

  • SMILES

    COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound