Eicosapentaenoic Acid sodium - CAS 73167-03-0

Eicosapentaenoic Acid (EPA) sodium, an orally active omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA), demonstrates a unique ability to demethylate DNA, thereby facilitating the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ) . This compound also activates the RAS/ERK/C/EBPβ pathway by demethylating H-Ras intron 1 CpG island in U937 leukemia cells and promotes the relaxation of vascular smooth muscle cells, leading to vasodilation.

Histone Demethylase, Others, Endogenous Metabolite

Chromatin/Epigenetic, Others, Metabolism

73167-03-0

C20H29NaO2

324.43

[Na+].CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC([O-])=O

-20°C

Ice Packs

Natural Product