EIF4A3-IN-1 - CAS 2095486-67-0

EIF4A3-IN-1 is a selective and potent inhibitor of eukaryotic initiation factor 4A3 (eIF4A3) with an IC50 value of 0.26 μM. eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.

PERK

Apoptosis

2095419

0.9989

C29H23BrClN5O2

588.88

C(=O)(N1[C@H](CN(C(=O)C2=C(C)N(N=C2)C3=CC(C#N)=CC=C3)CC1)C4=CC=C(Cl)C=C4)C5=CC=C(Br)C=C5

-20°C

Ice Packs

Small Compound