EIF4A3-IN-9 - CAS 1402931-71-8

EIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It is utilized in researching human cancer pathogenesis [1].

Others, PERK

Apoptosis, Others

1402852

C28H27NO8

505.52

O[C@]12[C@]([C@@H]([C@@H](C(OC)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(C(N)=O)C4)C5=CC=C(OC)C=C5

-20°C

Ice Packs

Small Compound