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EIF4E-IN-4 - CAS 1373822-39-9

EIF4E-IN-4 - CAS 1373822-39-9

SKU:MF-0114412-01

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  • Bioactivity

    EIF4E-IN-4 (Compound 33) is a selective inhibitor of the eukaryotic initiation factor 4E (eIF4E) with a biochemical activity value of 95 nM. It inhibits cap-dependent mRNA translation with an IC50 of 2.5 μM and is applicable in research on breast cancer, colon cancer, and head and neck cancer.

  • Target

    PERK

  • Related Pathways

    Apoptosis

  • CAS Number

    1373774

  • Molecular Formula

    C20H19ClN5O5P

  • Molecular Weight

    475.822

  • SMILES

    O=C1N=C(NC=2N=C(C=3C=CC(=CC3)P(=O)(O)O)N(C12)CCOC4=CC=C(Cl)C=C4)NC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound