Elabela (19-32) - CAS 1886973-05-2

Potent apelin (APJ) receptor agonist (Ki = 0.93 nM) . Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.

Arrestin, Apelin receptor

GPCR/G Protein

1886973-05-2

C75H119N25O17S2

1707.03

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CS)=O)CCSC)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)CC6=CC=CC=C6)=O)CCC4)[C@H](C)C)=O)CCCNC(=N)N)=O)CO)=O)=O)CC(C)C)=O)CCC2

-20°C

Ice Packs

Peptide