β-Elemonic Acid - CAS 28282-25-9

β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities.

COX, Prolyl Endopeptidase (PREP), Apoptosis, Reactive Oxygen Species, ROS, Endogenous Metabolite

Neuroscience, NF-κB, Immunology/Inflammation, Apoptosis, Metabolism, Proteases/Proteasome

28282-25-9

0.998

C30H46O3

454.68

CC(C)=CCC[C@@H]([C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1CC3)C(O)=O

-20°C

Ice Packs

Natural Product