Elenbecestat free base - CAS 1388149-39-0

Elenbecestat, also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.

Beta-Secretase, Others

Neuroscience, Others

1388110

C19H15F6N5O2S

491.41

C(F)(F)(F)[C@@H]1[C@@]2([C@](CO1)(N=C(N)SC2)C3=CC(NC(=O)C=4C=NC(C(F)F)=CN4)=CC=C3F)[H]

-20°C

Ice Packs

Small Compound