Eleven-Nineteen-Leukemia Protein IN-3 - CAS 2894121-83-4

Eleven-Nineteen-Leukemia Protein IN-3, an orally active ENL YEATS domain inhibitor, exhibits potent activity with an IC50 of 15.4 nM. It downregulates MYC expression via ENL in cells and enhances ENL protein's thermal stability in vitro [1].

Epigenetic Reader Domain

Chromatin/Epigenetic

2894034

C28H27N5O2

465.55

C[C@H]1CCCN1CC1=NC2=CC(NC(=O)C3=CC=C4C(=C3)C3=CC=CC=C3C(=O)N4C)=CC=C2N1

-20°C

Ice Packs

Small Compound