Elimusertib - CAS 1876467-74-1

Elimusertib (BAY-1895344) is a potent, highly selective, and orally available ATR inhibitor with an IC50 of 7 nM, demonstrating significant anti-tumor efficacy as a monotherapy and strong combination potential with targeted alpha therapy Radium-223 dichloride.

ATM/ATR

PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

1876392

0.9984

C20H21N7O

375.43

C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2ccnc(-c3cc[nH]n3)c2n1

-20°C

Ice Packs

Small Compound