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ELN318463 - CAS 851600-86-7
ELN318463 - CAS 851600-86-7
SKU:MF-0022210-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
ELN 318463 shows differential inhibition of presenilin (PS1) - and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
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Target
Others, Gamma-secretase
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Related Pathways
Stem Cells, Proteases/Proteasome, Others, Neuroscience
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CAS Number
851507
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Molecular Formula
C19H20BrClN2O3S
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Molecular Weight
471.8
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SMILES
Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)cc1)[C@@H]1CCCCNC1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound