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ELN318463 - CAS 851600-86-7

ELN318463 - CAS 851600-86-7

SKU:MF-0022210-01

Regular price $1,383.80 USD
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  • Bioactivity

    ELN 318463 shows differential inhibition of presenilin (PS1) - and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor.

  • Target

    Others, Gamma-secretase

  • Related Pathways

    Stem Cells, Proteases/Proteasome, Others, Neuroscience

  • CAS Number

    851507

  • Molecular Formula

    C19H20BrClN2O3S

  • Molecular Weight

    471.8

  • SMILES

    Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)cc1)[C@@H]1CCCCNC1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound