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Elomotecan hydrochloride - CAS 220997-99-9
Elomotecan hydrochloride - CAS 220997-99-9
SKU:MF-0152763
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Product Details
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Bioactivity
Elomotecan hydrochloride (BN 80927), a camptothecin analog from the homocamptothecin family (hCPT), is a highly potent inhibitor of both topoisomerases I and II. It demonstrates superior efficacy in reducing the proliferation of various tumor cells compared to other reference anticancer drugs targeting these topoisomerases.
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Target
Others, Topoisomerase
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Related Pathways
DNA Damage/DNA Repair, Others
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CAS Number
220889
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Molecular Formula
C29H33Cl2N3O4
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Molecular Weight
558.5
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SMILES
Cl.CC[C@@]1(O)CC(=O)OCc2c1cc1-c3nc4cc(Cl)c(C)cc4c(CN4CCC(C)CC4)c3Cn1c2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound