ELP-004 - CAS 15533-81-0

ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.

TRP/TRPV Channel

Membrane transporter/Ion channel

15452

C10H11Cl2NO

232.106

O=C(N(C1=CC=C(Cl)C(Cl)=C1)C)CC

-20°C

Ice Packs

Small Compound