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Eltanexor - CAS 1642300-52-4

Eltanexor - CAS 1642300-52-4

MF-0013886-01

$54.85 USD
$54.85 USD
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Product Details

  • Bioactivity

    Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines.

  • Target

    CRM1, Others

  • Related Pathways

    Others, Membrane transporter/Ion channel

  • CAS Number

    1642244

  • Purity

    0.9986

  • Molecular Formula

    C17H10F6N6O

  • Molecular Weight

    428.29

  • SMILES

    NC(=O)C(=C
    1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\c1cncnc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound