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Eltanexor Z-isomer - CAS 1642300-78-4

Eltanexor Z-isomer - CAS 1642300-78-4

MF-0022709-01

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Product Details

  • Bioactivity

    Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.

  • Target

    CRM1, Others

  • Related Pathways

    Membrane transporter/Ion channel, Others

  • CAS Number

    1642218

  • Molecular Formula

    C17H10F6N6O

  • Molecular Weight

    428.29

  • SMILES

    NC(=O)C(=C/n1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\c1cncnc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound