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Molfinity

Elubrixin - CAS 688763-64-6

Elubrixin - CAS 688763-64-6

SKU:MF-0013463-01

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  • Bioactivity

    Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM) . Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

  • Target

    IL Receptor, CXCR, Interleukin

  • Related Pathways

    GPCR/G Protein, Autophagy, Immunology/Inflammation

  • CAS Number

    688693

  • Purity

    >99.99%

  • Molecular Formula

    C17H17Cl2FN4O4S

  • Molecular Weight

    463.31

  • SMILES

    S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound