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Elubrixin - CAS 688763-64-6
Elubrixin - CAS 688763-64-6
SKU:MF-0013463-01
Regular price
$120.06 USD
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$120.06 USD
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Product Details
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Bioactivity
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM) . Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
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Target
IL Receptor, CXCR, Interleukin
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Related Pathways
GPCR/G Protein, Autophagy, Immunology/Inflammation
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CAS Number
688693
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Purity
>99.99%
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Molecular Formula
C17H17Cl2FN4O4S
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Molecular Weight
463.31
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SMILES
S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound