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Molfinity

EM127 - CAS 1886879-71-5

EM127 - CAS 1886879-71-5

MF-0109494-01

$110.31 USD
$110.31 USD
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Product Details

  • Bioactivity

    EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methyltransferase activity over a long period of time.EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors. EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors.

  • Target

    ERK, Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic, MAPK

  • CAS Number

    1886803

  • Purity

    0.9761

  • Molecular Formula

    C14H18ClN3O3

  • Molecular Weight

    311.76

  • SMILES

    ClCC(=O)N1CCC(CC1)NC(=O)c1cc(on1)C1CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound