Emapalumab - CAS 1709815-23-5

Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH) .

COX, IFNAR

Neuroscience, Immunology/Inflammation

1709787

0.9756

-20°C

Ice Packs

Inhibitory Antibodies