Emavusertib hydrochloride - CAS 2376399-42-5

Emavusertib (CA-4948) hydrochloride, a selective and potent IRAK4/FLT3 inhibitor, is designed for oral administration. It achieves an IC 50 of 57 nM against IRAK4 in a FRET kinase assay and demonstrates anti-tumor activity [1] [2] [3].

NF-κB, MyD88, IRAK, Apoptosis, FLT

Immunology/Inflammation, Angiogenesis, NF-κB, Tyrosine Kinase/Adaptors, Apoptosis

2376399-42-5

C24H26ClN7O5

527.96

N(C(=O)C=1N=C(OC1)C=2C=C(C)N=CC2)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CC[C@@H](O)C6.Cl

-20°C

Ice Packs

Small Compound