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EMD 527040 hydrochloride - CAS 2758431-92-2

EMD 527040 hydrochloride - CAS 2758431-92-2

SKU:MF-0041899

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  • Bioactivity

    EMD 527040 hydrochloride is an effective integrin αVβ6 inhibitor. The IC 50 values of EMD 527040 hydrochloride were 6 nM and 1.6 μM to inhibit αVβ6 binding to fibronectin and αVβ6 expression cells to fibronectin, respectively. EMD 527040 hydrochloride shows antifibrotic activity in animal models of biliary fibrosis and is active in vivo.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2758337

  • Molecular Formula

    C29H33Cl3N4O5

  • Molecular Weight

    623.96

  • SMILES

    O=C(CCCCNC1=CC=CC=N1)N[C@@H](COCC2=CC=CC=C2)C(NC(C3=CC(Cl)=CC(Cl)=C3)CC(O)=O)=O.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound