Molfinity

EML741 - CAS 2328074-38-8

SKU:MF-0022213

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Size 25 mg

Product Details

Bioactivity
EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b. EML741 exhibits low cell toxicity, and is membrane permeable and blood-brain barrier penetrated. EML741 is a histone lysine methyltransferase G9a/GLP inhibitor, with an IC50 of 23 nM, Kd of 1.13 μM for G9a.
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
CAS Number
2328028
Molecular Formula
C31H49N5O2
Molecular Weight
523.75
SMILES
N(C=1C=2C(N=C(CN1)C3CCCCC3)=CC(OCCCN4CCCC4)=C(OC)C2)C5CCN(C(C)C)CC5
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound