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Emofolin sodium - CAS 52386-42-2
Emofolin sodium - CAS 52386-42-2
SKU:MF-0141119-01
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Product Details
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Bioactivity
Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity, which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, depletion of nucleotide pools, and inhibition of DNA, RNA and protein synthesis.
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Target
Others, Antifolate
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Related Pathways
Cell Cycle/Checkpoint, Others
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CAS Number
52342
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Molecular Formula
C21H25N7Na2O6
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Molecular Weight
517.45
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SMILES
CN1C2=C(NC(N)=NC2=O)NCC1CCNC3=CC=C(C=C3)C(N[C@H](C([O-])=O)CCC([O-])=O)=O.[Na+].[Na+]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound