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Molfinity

EN1441 - CAS 2196448-47-0

EN1441 - CAS 2196448-47-0

MF-0114945-01

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Product Details

  • Bioactivity

    EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 μM, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.

  • Target

    Androgen Receptor

  • Related Pathways

    Endocrinology/Hormones

  • CAS Number

    2196401

  • Molecular Formula

    C13H13ClN2O2

  • Molecular Weight

    264.708

  • SMILES

    O=C(C=C)N1C2=CC(Cl)=CC=C2NC(=O)C1(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound