Enadoline (Free Base) - CAS 107431-28-7

Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S, S (-) -enantiomer; PD 129289 (CAM 569) is the corresponding R, R (+) -enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. There was mention of its potential in treating comatose head injury or stroke victims, where that type of side effect would be immaterial.

Opioid Receptor, Others

Neuroscience, Endocrinology/Hormones, GPCR/G Protein, Others

107396

C24H32N2O3

396.52

N(C(CC1=C2C(OC=C2)=CC=C1)=O)(C)C3C(CC4(CC3)CCCO4)N5CCCC5

-20°C

Ice Packs

Small Compound