Endoxifen mesylate - CAS 1032008-71-1

Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromatase inhibitors, and fulvestrant) . The prodrug tamoxifen is metabolized by the CYP2D6 enzyme to produce afimoxifene (4-hydroxytamoxifen) and endoxifen.

Others

Others

1031936

C26H31NO5S

469.59

S(C)(=O)(=O)O.C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCNC)C=C2)/C3=CC=C(O)C=C3

-20°C

Ice Packs

Small Compound