Ensifentrine - CAS 1884461-72-6

Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3 (IC50: 0.4 nM) is 3,440 times higher than that for PDE4 (IC50: 1479 nM), that is under clinical development for the treatment of asthma and COPD and, potentially, cystic fibrosis.

PDE

Metabolism

1884383

0.9994

C26H31N5O4

477.56

COc1cc2CCn3c(c\c(=N/c4c(C)cc(C)cc4C)n(CCNC(N)=O)c3=O)-c2cc1OC

-20°C

Ice Packs

Small Compound