Enzastaurin 2HCl - CAS 365253-37-8

Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) -stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.

PKC, Others, Autophagy, Apoptosis

Chromatin/Epigenetic, Apoptosis, Others, Autophagy, Cytoskeletal Signaling

365208

C32H31Cl2N5O2

588.53

O=C1C(C=2C=3C(N(C2)C4CCN(CC5=CC=CC=N5)CC4)=CC=CC3)=C(C(=O)N1)C=6C=7C(N(C)C6)=CC=CC7.Cl.Cl

-20°C

Ice Packs

Small Compound