Enzastaurin HCl - CAS 359017-79-1

Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) -stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.

Others, PKC, Autophagy, Apoptosis

Others, Cytoskeletal Signaling, Chromatin/Epigenetic, Apoptosis, Autophagy

358937

C32H30ClN5O2

552.08

Cl.Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCN(Cc4ccccn4)CC3)c3ccccc23)c2ccccc12

-20°C

Ice Packs

Small Compound