EP3 antagonist 4 - CAS 2408297-80-1

EP3 antagonist 4 is an EP3 antagonist that inhibits hEP with a Ki of 2 nM. EP3 antagonist 4 showed low in vivo clearance, high oral AUC and good bioavailability in complete PK studies in rats. EP3 antagonist 4 can be used to study diabetes and cellular dysfunction.

Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein

2408216

C22H20Cl3FN4O3S2

577.91

C(N1C\2=C(C=N1)CCC/C2=C(\CNC(NS(=O)(=O)C3=CC(C)=C(Cl)S3)=O)/F)C4=C(Cl)C=C(Cl)C=C4

-20°C

Ice Packs

Small Compound