EP3 antagonist 6 - CAS 499149-94-9

EP3 antagonist 6 (compound 5), a selective and orally active EP3 receptor antagonist, exhibits potent activity with an IC 50 of 1.9 nM. It effectively inhibits PGE2-induced uterine contractions in pregnant rats [1].

Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein

499149-94-9

C(N[C@H](CC(C)C)C1=CC(C)=CC(C)=C1)(=O)C2=C(CCC(O)=O)C=CC(COC3=C(C)C=CC=C3)=C2

-20°C

Ice Packs

Small Compound