Epaldeudomide - CAS 1918159-31-5

Epaldeudomide (Compound A406) is an inhibitor of TNF-α, showing an inhibition rate of over 50% at 100 nM. It effectively suppresses the proliferation of cancer cells MM.1S (IC50 < 300 nM), WSU-DLCL-2 (IC50 < 100 nM), and Rec-1 (IC50 < 100 nM) . Epaldeudomide exhibits antitumor activity.

TNF

Apoptosis

1918123

C25H26FN3O5

468.496

O(CC1=C(F)C=C(CN2CCOCC2)C=C1)C3=C4C(C(=O)N(C4)[C@@]5(C(=O)NC(=O)CC5)[2H])=CC=C3

-20°C

Ice Packs

Small Compound