Epertinib - CAS 908305-13-5

Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM) . It displays a strong antitumor activity.

EGFR, HER

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

908287

C30H27ClFN5O3

560.02

N(C=1C2=C(C=CC(\C(=N\OC[C@H]3COCCN3)\C#CC)=C2)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4

-20°C

Ice Packs

Small Compound