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Epertinib hydrochloride - CAS 2071195-74-7

Epertinib hydrochloride - CAS 2071195-74-7

MF-0011974-01

$93.25 USD
$54.60 USD $93.25 USD
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Product Details

  • Bioactivity

    Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.

  • Target

    EGFR, HER

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    2071195-74-7

  • Purity

    0.9936

  • Molecular Formula

    C30H28Cl2FN5O3

  • Molecular Weight

    596.48

  • SMILES

    Cl.CC#C\C(=N/OC[C@H]1COCCN1)c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound