Epicochlioquinone A - CAS 147384-57-4

Epicochlioquinone A inhibits rat liver microsomal ACAT with an IC50 of 1.7 μM and inhibits plasma lecithin-cholesterol acyltransferase (LCAT) with an IC50 of 15.8 μM. At a dosage of 75 mg/kg, it can reduce cholesterol absorption in rats by 50%.

Acyltransferase

Metabolism

147384-57-4

C30H44O8

532.666

C[C@@]12[C@@]3([C@@](C)(OC4=C([C@H]3O)C(=O)C=C([C@@H]([C@@H]([C@H](CC)C)OC(C)=O)C)C4=O)CC[C@]1(O[C@@H](C(C)(C)O)CC2)[H])[H]

-20°C

Ice Packs

Natural Product