Epimagnolin B - CAS 1134188-26-3

Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE (2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.

Prostaglandin Receptor, NF-κB, NO Synthase

Immunology/Inflammation, NF-κB, GPCR/G Protein

1134159

C23H28O7

416.46

[H][C@@]12CO[C@H](c3cc(OC)c(OC)c(OC)c3)[C@]1([H])CO[C@H]2c1cc(OC)cc(OC)c1

-20°C

Ice Packs

Natural Product