ER-076349 - CAS 253128-15-3

ER-076349 is a microtubule polymerization inhibitor that induces G2-M cell cycle arrest and disrupts mitotic spindles. This compound inhibits the growth of cancer cells and suppresses tumor growth in various human tumor xenograft mouse models. Additionally, ER-076349 is an analog of Halichondrin B.

Microtubule Associated

Cytoskeletal Signaling

253110

C40H58O12

730.88

C=C1C[C@@]2(CC[C@@]34O[C@@]5([C@]6([C@]([C@@](O3)([C@@](C4)(O6)[H])[H])(O[C@@]7([C@@]5(O[C@](CC7)(CC(=O)C[C@]8([C@@](O[C@H](C[C@@H](CO)O)[C@@H]8OC)(C[C@]9(O[C@@](CC[C@@]1(O2)[H])(C[C@@H](C)C9=C)[H])[H])[H])[H])[H])[H])[H])[H])[H])[H])[H]

-20°C

Ice Packs

Small Compound