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ER degrader 11 - CAS 2770911-29-8

ER degrader 11 - CAS 2770911-29-8

MF-0117808-01

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Product Details

  • Bioactivity

    ER degrader 11 (Compound 5) is an orally active, brain-penetrant, and selective estrogen receptor degrader, with an ERα IC50 of 1.6 nM. It holds potential for research into breast cancer brain metastasis.

  • Target

    Estrogen Receptor/ERR

  • Related Pathways

    Endocrinology/Hormones

  • CAS Number

    2770874

  • Molecular Formula

    C29H33F3N4

  • Molecular Weight

    494.59

  • SMILES

    C[C@H]1N(C23CC(C2)C3)[C@@H](C4=C(C1)C=5C(N4)=CC=CC5)C6=C(F)C=C(NC7CN(CCCF)C7)C=C6F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound