ERα degrader 13 - CAS 3070968-56-5

ERα degrader13 (compound MR3) is a potent ERα degrader with an IC50 of 0.55 μM. It demonstrates significant tumor regression effects in a breast cancer xenograft mouse model.

Estrogen Receptor/ERR

Endocrinology/Hormones

3070907

C50H48N4O5S2

849.07

C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCNC(CCCCCC/N=C/5\C=6C(C=7C(=C5)SC=8C(N7)=CC=C(N(CC)CC)C8)=CC=CC6)=O)C=C4

-20°C

Ice Packs

Small Compound