ERCC1-XPF-IN-1 - CAS 2411584-25-1

ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM), that inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic effects of UV radiation, and impedes DNA repair.

Others, DNA/RNA Synthesis

DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint

2411558

C28H32ClN5O2

506.04

N(C=1C2=C(N=C3C1C=C(O)C=C3)C=C(Cl)C=C2)C4=CC(CN5CCN(CCN(C)C)CC5)=C(O)C=C4

-20°C

Ice Packs

Small Compound