ERK-MYD88 interaction inhibitor 1 - CAS 2215927-89-0

ERK-MYD88 Interaction Inhibitor 1, an agent that disrupts the interaction between ERK and MYD88, has demonstrated the ability to trigger an HRI-mediated integrated stress response (ISR) that specifically promotes immunogenic cell apoptosis (apoptosis) in cancer cells. Additionally, in models using Lewis lung cancer mice, this compound has been shown to stimulate anti-tumor T cell responses, thereby exhibiting significant anti-tumor activity.

Apoptosis

Apoptosis

2215838

C22H21N5O2

387.43

O=C(NC1=CN=C(OC)C=C1)C2=CC=C3N=C(NC3=C2)C=4C=CC(=CC4)N(C)C

-20°C

Ice Packs

Small Compound