ERK2/p38α MAPK-IN-1 - CAS 1016427-72-7

ERK2/p38α MAPK-IN-1 (Compound 1, In silico Hit-2), a selective inhibitor of ERK2 and p38α MAPK, exhibits potent activity with an IC 50 of 82 μM against ERK2. It uniquely binds to the allosteric sites of both ERK2 and p38α MAPK. This compound is utilized for type 2 diabetes research [1].

P38 MAPK, ERK

MAPK

1016427-72-7

C20H16FN3O4S2

445.49

O(C)C=1C=C2C(=CC1OC)SC(NC(=O)C=3N=C(COC4=CC=C(F)C=C4)SC3)=N2

-20°C

Ice Packs

Small Compound