ErSO-TFPy - CAS 3035547-78-2

ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.

Sodium Channel

Membrane transporter/Ion channel

3035467

C19H13F7N2O2

434.307

O=C1[C@@](C=2C(N1)=C(C(F)(F)F)C=CC2)(N3CC(F)(F)C(F)(F)C3)C4=CC=C(O)C=C4

-20°C

Ice Packs

Small Compound