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Esorubicin - CAS 63521-85-7
Esorubicin - CAS 63521-85-7
SKU:MF-0143706-01
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Product Details
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Bioactivity
Esorubicin is a synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause more severe myelosupression compared to other compounds within the anthracycline class. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .
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Target
Others
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Related Pathways
Others
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CAS Number
63429
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Molecular Formula
C27H29NO10
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Molecular Weight
527.52
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SMILES
OC=1C2=C([C@@H](O[C@H]3C[C@H](N)C[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=C(OC)C=CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound