EST73502 hydrochloride - CAS 2307458-82-6

EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K i s of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 hydrochloride has antinociceptive activity with reduced opioid-induced relevant adverse events[1].

Opioid Receptor, Others, Sigma receptor

GPCR/G Protein, Neuroscience, Endocrinology/Hormones, Others

2307370

C19H27ClF2N2O2

388.88

CCN1CC2(CCN(CCC3=CC(F)=CC=C3F)CC2)O[C@H](C)C1=O

-20°C

Ice Packs

Small Compound