Etomoxir - CAS 124083-20-1

Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM) . Etomoxir inhibits fatty acid oxidation by inhibiting CPT-1a, inhibits palmitate oxidation, has an inhibitory effect on adenine nucleotide translocase, and can inhibit macrophage polarization by disrupting CoA homeostasis.

Apoptosis, Antioxidant, CPT

Oxidation-Reduction, Apoptosis, Metabolism

124062

0.9939

C17H23ClO4

326.82

C(OCC)(=O)[C@@]1(CCCCCCOC2=CC=C(Cl)C=C2)CO1

-20°C

Ice Packs

Small Compound