Etoposide phosphate disodium - CAS 122405-33-8

Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, is a potent chemotherapeutic agent that selectively inhibits topoisomerase II, hindering the re-ligation of DNA strands. Regarded as the active equivalent of etoposide, it effectively induces cell cycle arrest, apoptosis, and autophagy in cancer cells.

Topoisomerase, Others, Autophagy, Apoptosis

DNA Damage/DNA Repair, Apoptosis, Autophagy, Others

122364

C29H31Na2O16P

712.5

[Na].[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OP(O)(O)=O)c(OC)c1)c1cc3OCOc3cc1[C@H]2O[C@@H]1O[C@]2([H])CO[C@@H](C)O[C@@]2([H])[C@H](O)[C@H]1O

-20°C

Ice Packs

Small Compound