Etravirine - CAS 269055-15-4

Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.

Reverse Transcriptase, HIV Protease

Microbiology/Virology, Proteases/Proteasome

269036

0.9974

C20H15BrN6O

435.28

O(C1=NC(NC2=CC=C(C#N)C=C2)=NC(N)=C1Br)C3=C(C)C=C(C#N)C=C3C

-20°C

Ice Packs

Small Compound