γ-Eudesmol - CAS 1209-71-8

γ-Eudesmol ((+) -γ-Eudesmol) is a compound that induces apoptosis through mitochondrial pathways. It binds to mitochondrial membrane proteins, causing depolarization of the mitochondrial membrane potential and activates the caspase cascade. This compound exhibits cytotoxicity against various tumor cell lines, such as HepG2 and B16-F10, with IC50 values ranging from 8.86 to 15.15 μg/mL. γ-Eudesmol holds potential for research in cancers including hepatocellular carcinoma and melanoma.

Apoptosis

Apoptosis

1209-71-8

C15H26O

222.37

C[C@]12C(C[C@H](C(C)(C)O)CC1)=C(C)CCC2

-20°C

Ice Packs

Natural Product