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Molfinity

Eupolauridine - CAS 58786-39-3

Eupolauridine - CAS 58786-39-3

MF-0124441-01

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Product Details

  • Bioactivity

    Eupolauridine is a selective DNA topoisomerase II inhibitor, exhibiting an IC50 of 20 μM against fungal topoisomerase I and 33 μM for human topoisomerase I. By inhibiting the catalytic activity of topoisomerase II, Eupolauridine stabilizes the enzyme's cleavage complex with DNA, resulting in DNA damage and imparting antifungal activity. [Eupolauridine] holds potential for the study of fungal infectious diseases.

  • Target

    Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair

  • CAS Number

    58786-39-3

  • Molecular Formula

    C14H8N2

  • Molecular Weight

    204.23

  • SMILES

    N=1C=CC2=CC=NC=3C=4C=CC=CC4C1C23

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product